产品
编 号:F462352
分子式:C31H38N4O5S
分子量:578.72
产品类型
结构图
CAS No: 797035-11-1
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产品详情
生物活性:
β-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively.
体外研究:
In the cell culture assay, β-Secretase Inhibitor IV (Compound 2) inhibits the production of Aβ peptides with an EC50 of 43 nM. β-Secretase Inhibitor IV potently suppresses the secretion of sAPP_NF and EV40 from HEK293T cells with an IC50 near 30 nM.