产品
编 号：F462099
分子式：C38H54ClN3O10S
分子量：780.37
分子式：C38H54ClN3O10S
分子量：780.37
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
328
In-stock
5mg
720
In-stock
10mg
1320
In-stock
50mg
4400
In-stock
结构图
CAS No: 796073-69-3
产品详情
生物活性：
DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody agent conjugate.
体外研究：
DM4, a structural analogue of maytansine, is a new thiol-containing and potent maytansinoid. DM4 is a cytotoxic maytansinoid drug. It is synthesized in order to link maytansinoids to antibodies via disulfide bonds. Maytansinoids inhibit tubulin polymerization and microtubule assembly and enhance microtubule destabilization, so there is potent suppression of microtubule dynamics resulting in a mitotic block and subsequent apoptotic cell death.
DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody agent conjugate.
体外研究：
DM4, a structural analogue of maytansine, is a new thiol-containing and potent maytansinoid. DM4 is a cytotoxic maytansinoid drug. It is synthesized in order to link maytansinoids to antibodies via disulfide bonds. Maytansinoids inhibit tubulin polymerization and microtubule assembly and enhance microtubule destabilization, so there is potent suppression of microtubule dynamics resulting in a mitotic block and subsequent apoptotic cell death.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备