产品
编 号:F460706
分子式:C17H20ClNO
分子量:289.8
产品类型
结构图
CAS No: 791-35-5
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产品详情
生物活性:
Chlophedianol (Clofedanol) is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs).
体内研究:
Chlophedianol hydrochloride (0-162 mg/kg; p.o. or s.c.; once) lowers the volume output of respiratory tract fluid in rabbits and cats.Animal Model:Healthy, adult, male rabbits and cats
Dosage:2.0, 6.0, 18, 54 and 162 mg/kg (PO) or 1.0, 3.0, 9.0, 27 and 81 mg/kg (SC)
Administration:Oral or subcutaneous administration, once
Result:Lowered the volume output of respiratory tract fluid, slightly but significantly over a period of one to three hours after administration. Produced a decrease in the number of animals in which pledgets of mucus appeared in the respiratory tract.