产品
编 号：F459743
分子式：C18H14ClF3N4O2S
分子量：442.84
分子式：C18H14ClF3N4O2S
分子量：442.84
产品类型
规格
价格
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结构图
CAS No: 787623-48-7
产品详情
生物活性：
COX-2-IN-1 is potent and slective COX-2 inhibitor with an IC50 of 3.9 μM.
体外研究：
COX-2-IN-1(compound5f) is an inhibitor of COX-1 and COX-2 withIC50sof>100 and 3.9 μM, respctively. Comparison of 5b and COX-2-IN-1 shows that smaller halogen atom at 5th position on the indole ring enhances COX-2 enzyme inhibition activity, whereas the presence of a larger bromine atom at 6th position of the ring improves the inhibitory activity (5d, 5e and 5h) of the compound.
COX-2-IN-1 is potent and slective COX-2 inhibitor with an IC50 of 3.9 μM.
体外研究：
COX-2-IN-1(compound5f) is an inhibitor of COX-1 and COX-2 withIC50sof>100 and 3.9 μM, respctively. Comparison of 5b and COX-2-IN-1 shows that smaller halogen atom at 5th position on the indole ring enhances COX-2 enzyme inhibition activity, whereas the presence of a larger bromine atom at 6th position of the ring improves the inhibitory activity (5d, 5e and 5h) of the compound.
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