产品
编 号：F459336
分子式：C21H36ClNO
分子量：353.97
分子式：C21H36ClNO
分子量：353.97
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
440
In-stock
200mg
720
In-stock
结构图
CAS No: 78613-38-4
产品详情
生物活性：
Amorolfine (Ro 14-4767/002) hydrochloride is a potent anti-fungal agent. Amorolfine hydrochloride inhibits ergosterol biosynthesis. Amorolfine hydrochloride has the potential for the research of Neoscytalidium dimidiatum onychomycosis.
体内研究：
Amorolfine hydrochloride (0.01%-1%; Intravaginal application; twice daily for 3 days) shows anti-fungal activity in rats with vaginal candidiasis.Animal Model:Rats (vaginal candidiasis)
Dosage:0.01%-1%
Administration:Intravaginal application; twice daily for 3 days
Result:Produced a dose dependent log reduction in cell count; a concentration of 1 % cleared the vagina of C. albicans completely.
体外研究：
Amorolfine hydrochloride acts primarily by inhibiting ergosterol biosynthesis, a component of fungal cell membrane, and possesses both fungistatic and fungicidal activity.Amorolfine hydrochloride (0-128 mg/l) (2-7 days) shows anti-fungal activity for Dermatophyte fungi, Filamentous fungi, Pathogenic yeasts, Dimorphic fungi, Dematiaceous fungi.Amorolfine hydrochloride shows anti-fungal activity with 90% killing corresponding concentrations of 3, 3, 10 and 100 mg/L for Trichophyton mentagrophytes, C. albicans, Histoplasma capsulatum, Cryptococcus neoformans, respectively.
Amorolfine (Ro 14-4767/002) hydrochloride is a potent anti-fungal agent. Amorolfine hydrochloride inhibits ergosterol biosynthesis. Amorolfine hydrochloride has the potential for the research of Neoscytalidium dimidiatum onychomycosis.
体内研究：
Amorolfine hydrochloride (0.01%-1%; Intravaginal application; twice daily for 3 days) shows anti-fungal activity in rats with vaginal candidiasis.Animal Model:Rats (vaginal candidiasis)
Dosage:0.01%-1%
Administration:Intravaginal application; twice daily for 3 days
Result:Produced a dose dependent log reduction in cell count; a concentration of 1 % cleared the vagina of C. albicans completely.
体外研究：
Amorolfine hydrochloride acts primarily by inhibiting ergosterol biosynthesis, a component of fungal cell membrane, and possesses both fungistatic and fungicidal activity.Amorolfine hydrochloride (0-128 mg/l) (2-7 days) shows anti-fungal activity for Dermatophyte fungi, Filamentous fungi, Pathogenic yeasts, Dimorphic fungi, Dematiaceous fungi.Amorolfine hydrochloride shows anti-fungal activity with 90% killing corresponding concentrations of 3, 3, 10 and 100 mg/L for Trichophyton mentagrophytes, C. albicans, Histoplasma capsulatum, Cryptococcus neoformans, respectively.
产品资料
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