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编 号：F459018
分子式：C18H16O4
分子量：296.32
分子式：C18H16O4
分子量：296.32
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CAS No: 78499-27-1
产品详情
生物活性：
Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory agent. Bermoprofen has potent antipyretic activities with a short biological half-life. Bermoprofen is a potent antagonist of LPS-induced fever in rabbits.
体内研究：
Bermoprofen (AD-1590) (0.04-0.1 mg/kg; p.o.) shows a dose-related antipyretic activity in LPS-induced febrile rabbits.Animal Model:Male albino rabbits, 2.3-3 kg
Dosage:0.04, 0.4, 0.1 mg/kg
Administration:Oral; given 1 h after i.v. injection of LPS
Result:Inhibited significantly the rise in rectal temperature at doses of 0.1 mg/kg or more, the temperature returned approximately to normal after 0.4 mg/kg.
体外研究：
Bermoprofen (AD-1590) shows ulcerogenic activity as a side-effect like other nonsteroidal anti-inflammatory agents.
Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory agent. Bermoprofen has potent antipyretic activities with a short biological half-life. Bermoprofen is a potent antagonist of LPS-induced fever in rabbits.
体内研究：
Bermoprofen (AD-1590) (0.04-0.1 mg/kg; p.o.) shows a dose-related antipyretic activity in LPS-induced febrile rabbits.Animal Model:Male albino rabbits, 2.3-3 kg
Dosage:0.04, 0.4, 0.1 mg/kg
Administration:Oral; given 1 h after i.v. injection of LPS
Result:Inhibited significantly the rise in rectal temperature at doses of 0.1 mg/kg or more, the temperature returned approximately to normal after 0.4 mg/kg.
体外研究：
Bermoprofen (AD-1590) shows ulcerogenic activity as a side-effect like other nonsteroidal anti-inflammatory agents.
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