产品
编 号：F457377
分子式：C9H12O4
分子量：184.19
分子式：C9H12O4
分子量：184.19
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 778649-18-6
产品详情
生物活性：
Butyrolactone 3 (MB-3) is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 μM), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 shows weak inhibitory on CBP (IC50=0.5 mM). Butyrolactone 3 can be used in studies of cancer, metabolic, autoimmune and neurological diseases.
体外研究：
Butyrolactone 3 (50, 100, 200 μM, 16 h) 可降低 Gcn5 乙酰化并诱导 E2A-PBX1 降解。
Butyrolactone 3 (MB-3) is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 μM), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 shows weak inhibitory on CBP (IC50=0.5 mM). Butyrolactone 3 can be used in studies of cancer, metabolic, autoimmune and neurological diseases.
体外研究：
Butyrolactone 3 (50, 100, 200 μM, 16 h) 可降低 Gcn5 乙酰化并诱导 E2A-PBX1 降解。
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