产品
编 号：F456696
分子式：C21H24O6
分子量：372.41
分子式：C21H24O6
分子量：372.41
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
104
In-stock
5mg
209
In-stock
10mg
335
In-stock
50mg
720
In-stock
100mg
960
In-stock
结构图
CAS No: 7770-78-7
产品详情
生物活性：
Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions.
体内研究：
Arctigenin (250 μg/mL; 0.2 mL; i.p. 6 times a week for 9 weeks) suppress the PANC-1 tumor growth in nude mice.?Arctigenin (10 mg/kg; i.p. daily for 30 days) relieves experimental autoimmune encephalomyelitis (EAE) symptoms of mice.Animal Model:Female SPF/VAF BALB/cAn Ncrj-nu/nu mice were injected with PANC-1 cells
Dosage:250 μg/mL, 0.2 mL
Administration:I.p. 6 times a week for 9 weeks
Result:Reduced the tumor weight and volume.No significant body weight loss was recognized.
体外研究：
Arctigenin (0.01-1 μg/mL; 0.5-24 h) shows preferential cytotoxicity against the PANC-1 cell line under nutrient-deprived conditions in a concentration- and time-dependent manner.?Arctigenin (0.01-1 μg/mL; 0.5-24 h) inhibits the survival of various cancer cell lines (ASPC-1, BXPC-3, Alexander, and PSN-1 cells) under nutrient-deprived conditions.?Arctigenin (0.1-1 μg/mL; 24 h) completely inhibits Akt phosphorylation stimulated by glucose deprivation in PANC-1 cells.?Arctigenin (5-25 μM) shows potent in vitro antiviral activities (IC50=2.9 μM) against influenza A virus.
Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions.
体内研究：
Arctigenin (250 μg/mL; 0.2 mL; i.p. 6 times a week for 9 weeks) suppress the PANC-1 tumor growth in nude mice.?Arctigenin (10 mg/kg; i.p. daily for 30 days) relieves experimental autoimmune encephalomyelitis (EAE) symptoms of mice.Animal Model:Female SPF/VAF BALB/cAn Ncrj-nu/nu mice were injected with PANC-1 cells
Dosage:250 μg/mL, 0.2 mL
Administration:I.p. 6 times a week for 9 weeks
Result:Reduced the tumor weight and volume.No significant body weight loss was recognized.
体外研究：
Arctigenin (0.01-1 μg/mL; 0.5-24 h) shows preferential cytotoxicity against the PANC-1 cell line under nutrient-deprived conditions in a concentration- and time-dependent manner.?Arctigenin (0.01-1 μg/mL; 0.5-24 h) inhibits the survival of various cancer cell lines (ASPC-1, BXPC-3, Alexander, and PSN-1 cells) under nutrient-deprived conditions.?Arctigenin (0.1-1 μg/mL; 24 h) completely inhibits Akt phosphorylation stimulated by glucose deprivation in PANC-1 cells.?Arctigenin (5-25 μM) shows potent in vitro antiviral activities (IC50=2.9 μM) against influenza A virus.
产品资料
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