产品
编 号：F456431
分子式：C11H10Cl2N4
分子量：269.13
分子式：C11H10Cl2N4
分子量：269.13
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 7761-45-7
产品详情
生物活性：
Metoprine (BW 197U) is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT. Metoprine is an antifolate and antitumor agent.
体内研究：
Metoprine (BW 197U; 2-10 mg/kg; IP) ameliorates the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner.Intraperitoneal administration of Metoprine produces various behavioral effects, including decreases in food intake and increases in water consumption. Animal Model:Male Sprague-dawley rats (200-280g)
Dosage:2, 5, 10 mg/kg
Administration:IP
Result:Ameliorated the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner and significanty prolonged transfer latency at a high dose of 10 mg/kg.
Metoprine (BW 197U) is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT. Metoprine is an antifolate and antitumor agent.
体内研究：
Metoprine (BW 197U; 2-10 mg/kg; IP) ameliorates the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner.Intraperitoneal administration of Metoprine produces various behavioral effects, including decreases in food intake and increases in water consumption. Animal Model:Male Sprague-dawley rats (200-280g)
Dosage:2, 5, 10 mg/kg
Administration:IP
Result:Ameliorated the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner and significanty prolonged transfer latency at a high dose of 10 mg/kg.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备