产品
编 号:F456390
分子式:C15H10O4
分子量:254.24
产品类型
结构图
CAS No: 7758-73-8
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产品详情
生物活性:
LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
体外研究:
LC3-mHTT-IN-AN2 (10, 50, 100, and 300 nM) reduces the levels of mHTT in an allele-selective manner in cultured HD mouse neurons.