产品
编 号:F456106
分子式:C11H11N5
分子量:213.24
产品类型
结构图
CAS No: 77500-04-0
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产品详情
生物活性:
MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors.
体内研究:
MeIQx (2.0-200 mg/kg; i.p.; male Swiss Webster mice) is in the covalent binding to hemoglobin in a dose-dependent manner.Animal Model:Male Swiss Webster mice
Dosage:2.0-200 mg/kg
Administration:Intraperitoneal injection
Result:Increased the covalent binding to hemoglobin in a dose-dependent manner.
体外研究:
MeIQx (0.47 mM; 0-120 min) binds covalently to mouse hemoglobin and is activated by mouse microsomes to metabolites.