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编 号:F456075
分子式:C7H13N3O4S
分子量:235.26
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生物活性:
GEMSA is a potent inhibitor of enkephalin convertase (Ki=8.8 nM). GEMSA elicites analgesia.

体内研究:
GEMSA (ICV, 0.1μg/mg, every, 3days) results in a 75% increase in hypothalamic luteinizing hormone-releasing hormone and serum luteinizing hormone levels, and a 60% decrease in serum prolactin concentrations in rat

体外研究:
GEMSA inhibits the activation of TAFI and porcine CBB.GEMSA can inhibit the prolongation of lysis time in recombinant BAP and does not lead to the lysis of APC fibronectin.GEMSA inhibits the prolongation of lysis time in porcine CPB, TAFI, and recombinant BAP, APC with the EC50 values of 0.34 μM, 100μM, 115 μM, 90 μM respectively.
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