产品
编 号:F455929
分子式:C53H77N13O11S2
分子量:1136.39
产品类型
结构图
CAS No: 77453-01-1
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产品详情
生物活性:
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP.
体内研究:
SKF 100398 is a specific antagonist of the hydrosmotic effect of exogenous and endogenous AVP.SKF 100398 (8 μg/kg; i.v.) abolishes the antidiuretic effect of AVP.Animal Model:Male Sprague-Dawley rats (250-300 g)
Dosage:8 μg/kg
Administration:Intravenous injection
Result:Completely blocked the antidiuretic effect of exogenous AVP (4 ng/kg body wt i.v.).