产品
编 号:F455157
分子式:C25H24O12
分子量:516.45
产品类型
结构图
CAS No: 77307-50-7
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产品详情
生物活性:
SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC50 of 89 nM. SL 0101-1 (SL0101) is a selective RSK1/2 inhibitor, with a Ki of 1 μM.
体外研究:
SL 0101-1 (SL0101) shows proliferation inhibition in human breast cancer cell line MCF-7 and produces a cell cycle block in G1 phase.