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编 号：F454272
分子式：C28H39ClO8
分子量：539.06
分子式：C28H39ClO8
分子量：539.06
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CAS No: 77011-63-3
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生物活性：
Beclometasone dipropionate monohydrate, the proagent of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate monohydrate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate monohydrate can be used for asthma .
体内研究：
Beclometasone dipropionate monohydrate (150 μg/kg; nebulization; male BALB/c mice) relieves asthma and decreases total cell number and relative eosinophil number.Animal Model:Male BALB/c mice with asthma
Dosage:150 μg/kg
Administration:Nebulization
Result:Decreased total cell number and relative eosinophil number in BALF.
体外研究：
Beclometasone dipropionate monohydrate (1-100 nM; 20 min) inhibits STAT-1 expression and reduces the levels of iNOS, ROS and NT generated by rhIL-17A in 16HBE cells.
Beclometasone dipropionate monohydrate, the proagent of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate monohydrate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate monohydrate can be used for asthma .
体内研究：
Beclometasone dipropionate monohydrate (150 μg/kg; nebulization; male BALB/c mice) relieves asthma and decreases total cell number and relative eosinophil number.Animal Model:Male BALB/c mice with asthma
Dosage:150 μg/kg
Administration:Nebulization
Result:Decreased total cell number and relative eosinophil number in BALF.
体外研究：
Beclometasone dipropionate monohydrate (1-100 nM; 20 min) inhibits STAT-1 expression and reduces the levels of iNOS, ROS and NT generated by rhIL-17A in 16HBE cells.
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