产品
编 号：F454111
分子式：C12H21N5O2S2
分子量：331.46
分子式：C12H21N5O2S2
分子量：331.46
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1g
240
In-stock
5g
448
In-stock
结构图
CAS No: 76963-41-2
产品详情
生物活性：
Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach?and?intestines ulcers. Nizatidine works by decreasing the secretion of gastric?acid the stomach makes and prevent ulcers from coming back after they have healed in animal models.
体内研究：
Nizatidine (oral gavage; 27 mg/kg; once daily; at 12 weeks of age and were sacrificed at 30 weeks after development of HCC in the setting of nonalcoholic steatohepatitis (NASH)) results in a 35% reduction of tumor nodules relative to controls. Nizatidine results in a 60% reduction in tumor nodules, reduces collagen proportional area and expression of profibrotic markers in?DEN-injured rats.Nizatidine (oral gavage; 27 mg/kg; once daily; 4 weeks) decreases the incidence of gastric ulceration, and significantly decreases the mean ulcer score and ulcer index in male albino rats.Animal Model:Male albino rats
Dosage:27 mg/kg
Administration:Oral gavage; 27 mg/kg; once daily; 4 weeks
Result:Was effective in the management of NSAIDs induced peptic ulcer in rats.
Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach?and?intestines ulcers. Nizatidine works by decreasing the secretion of gastric?acid the stomach makes and prevent ulcers from coming back after they have healed in animal models.
体内研究：
Nizatidine (oral gavage; 27 mg/kg; once daily; at 12 weeks of age and were sacrificed at 30 weeks after development of HCC in the setting of nonalcoholic steatohepatitis (NASH)) results in a 35% reduction of tumor nodules relative to controls. Nizatidine results in a 60% reduction in tumor nodules, reduces collagen proportional area and expression of profibrotic markers in?DEN-injured rats.Nizatidine (oral gavage; 27 mg/kg; once daily; 4 weeks) decreases the incidence of gastric ulceration, and significantly decreases the mean ulcer score and ulcer index in male albino rats.Animal Model:Male albino rats
Dosage:27 mg/kg
Administration:Oral gavage; 27 mg/kg; once daily; 4 weeks
Result:Was effective in the management of NSAIDs induced peptic ulcer in rats.
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