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编 号：F454094
分子式：C19H29N5O2
分子量：359.47
分子式：C19H29N5O2
分子量：359.47
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CAS No: 76956-02-0
产品详情
生物活性：
Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia.
体内研究：
Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice. Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice. Animal Model:Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis
Dosage:0.5 g/L
Administration:Orally (drinking water); changed weekly; for 3 months
Result:Showed partial suppression of both gastric acid secretion and progression to neoplasia.
Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia.
体内研究：
Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice. Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice. Animal Model:Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis
Dosage:0.5 g/L
Administration:Orally (drinking water); changed weekly; for 3 months
Result:Showed partial suppression of both gastric acid secretion and progression to neoplasia.
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