产品
编 号：F452514
分子式：C18H24N2O5
分子量：348.39
分子式：C18H24N2O5
分子量：348.39
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CAS No: 76420-72-9
产品详情
生物活性：
Enalaprilat (MK-422 anhydrous), the active metabolite of the oral proagent Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor, with an IC50 of 1.94 nM. Enalaprilat can be used for the research of hypertension.
体内研究：
Enalaprilat (0.01%-2.9% in the eyedrop solution) shows significant intraocular pressure (IOP)-lowering effect in rabbits.
体外研究：
Enalaprilat (1 nM-10 μM; 24 h) attenuates the IGF-I induced neonatal rat cardiac fibroblast growth (30% reduction) in a concentration-dependent fashion, with an IC50 of 90 mM.
Enalaprilat (MK-422 anhydrous), the active metabolite of the oral proagent Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor, with an IC50 of 1.94 nM. Enalaprilat can be used for the research of hypertension.
体内研究：
Enalaprilat (0.01%-2.9% in the eyedrop solution) shows significant intraocular pressure (IOP)-lowering effect in rabbits.
体外研究：
Enalaprilat (1 nM-10 μM; 24 h) attenuates the IGF-I induced neonatal rat cardiac fibroblast growth (30% reduction) in a concentration-dependent fashion, with an IC50 of 90 mM.
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