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编 号：F452027
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CAS No: 762260-74-2
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生物活性：
Efungumab is a monoclonal antibody with antifungal activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC).
体内研究：
Efungumab (2 mg/kg， i.p.， 每日一次， 持续三天) 在 CD1 小鼠念珠菌 c. albicans 传播性模型中显著降低器官上菌株的平均集落个数，并增加肝活检阴性结果。Animal Model:CD1 mice models of disseminated c. albicans disease
Dosage:2 mg/kg, daily for 3 days
Administration:Intraperitoneal injection (i.p.)
Result:Decreased mean organ colony counts and increased negative liver biopsies for many of the isolates.
Efungumab is a monoclonal antibody with antifungal activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC).
体内研究：
Efungumab (2 mg/kg， i.p.， 每日一次， 持续三天) 在 CD1 小鼠念珠菌 c. albicans 传播性模型中显著降低器官上菌株的平均集落个数，并增加肝活检阴性结果。Animal Model:CD1 mice models of disseminated c. albicans disease
Dosage:2 mg/kg, daily for 3 days
Administration:Intraperitoneal injection (i.p.)
Result:Decreased mean organ colony counts and increased negative liver biopsies for many of the isolates.
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