产品
编 号:F451836
分子式:C16H8Cl4N2O2
分子量:402.06
产品类型
结构图
CAS No: 76150-91-9
联系客服
产品详情
生物活性:
TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss. TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins.
体内研究:
TCPOBOP (oral; 3 mg/kg; 1-5 days) remarkable increases Liver weight to body weight in LW/BW ratio at 48 hours.Animal Model:METfl/fl: Tam-Cre+/+ mice with a targeted deletion for exon 16 with MET KO
Dosage:3 mg/kg
Administration:Oral; 1, 2, 5 days
Result:Increased Liver weight to body weight.