产品
编 号：F451313
分子式：C16H21N3O5S
分子量：367.42
分子式：C16H21N3O5S
分子量：367.42
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CAS No: 75975-70-1
产品详情
生物活性：
Cephradine (Cefradine) monohydrate is a broad-spectrum and orally active cephalosporin. Cephradine monohydrate is active against both grampositive and gram-negative pathogens and effective in eradicating most penicillinase-producing organisms known to be resistant to penicillin G, penicillin V, and ampicillin. Cephradine monohydrate has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine monohydrate blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK.
体内研究：
Cephradine (25 mg/kg; s.c.; 11 days) reduces the bacterial density and counts in the abscesses.Animal Model:Nondiabetic mice
Dosage:25 mg/kg
Administration:S.c.; 11 days
Result:Reduced the bacterial density and counts in the abscesses.
体外研究：
Cephradine (0~8 μg/mL; 12 hours) makes bacterial viability rapidly increased at antibiotic concentrations below the MIC (minimum inhibitory concentration) of 0.70 μg/mL at both pH 7.4 and pH 5.5.
Cephradine (Cefradine) monohydrate is a broad-spectrum and orally active cephalosporin. Cephradine monohydrate is active against both grampositive and gram-negative pathogens and effective in eradicating most penicillinase-producing organisms known to be resistant to penicillin G, penicillin V, and ampicillin. Cephradine monohydrate has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine monohydrate blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK.
体内研究：
Cephradine (25 mg/kg; s.c.; 11 days) reduces the bacterial density and counts in the abscesses.Animal Model:Nondiabetic mice
Dosage:25 mg/kg
Administration:S.c.; 11 days
Result:Reduced the bacterial density and counts in the abscesses.
体外研究：
Cephradine (0~8 μg/mL; 12 hours) makes bacterial viability rapidly increased at antibiotic concentrations below the MIC (minimum inhibitory concentration) of 0.70 μg/mL at both pH 7.4 and pH 5.5.
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