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编 号：F450988
分子式：C20H28N2O5
分子量：376.45
分子式：C20H28N2O5
分子量：376.45
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CAS No: 75847-73-3
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生物活性：
Enalapril (MK-421) is an angiotensin-converting enzyme (ACE) inhibitor, can be used for hypertensive diseases research.
体内研究：
Enalapril (intraperitoneal injection, 0.03 mg/kg, once, 1 hour) reduces infarct volume due to middle cerebral artery occlusion and lower or higher doses are ineffective in Male NMRI mice.Animal Model:Male NMRI mice 20-40 g
Dosage:0.03 mg/kg
Administration:Intraperitoneal injection; once
Result:Reduced the area of middle cerebral artery infarction in mice at 0.03 mg/kg.
体外研究：
Enalapril (10-20 μM) has an antiarrhythmic effect in ultrafiltered PV sleeve preparation isolated from canine hearts which can inhibit EAD and DAD-induced activity.Enalapril (50 μM, 24 hours) inhibits the induction of apoptosis by patient serum only when used prior to treatment of HUVEC with Alzheimer's disease (AD) serum.Pure Enalapril has better thermal stability than pure Enalapril.
Enalapril (MK-421) is an angiotensin-converting enzyme (ACE) inhibitor, can be used for hypertensive diseases research.
体内研究：
Enalapril (intraperitoneal injection, 0.03 mg/kg, once, 1 hour) reduces infarct volume due to middle cerebral artery occlusion and lower or higher doses are ineffective in Male NMRI mice.Animal Model:Male NMRI mice 20-40 g
Dosage:0.03 mg/kg
Administration:Intraperitoneal injection; once
Result:Reduced the area of middle cerebral artery infarction in mice at 0.03 mg/kg.
体外研究：
Enalapril (10-20 μM) has an antiarrhythmic effect in ultrafiltered PV sleeve preparation isolated from canine hearts which can inhibit EAD and DAD-induced activity.Enalapril (50 μM, 24 hours) inhibits the induction of apoptosis by patient serum only when used prior to treatment of HUVEC with Alzheimer's disease (AD) serum.Pure Enalapril has better thermal stability than pure Enalapril.
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