产品
编 号:F448792
分子式:C11H14Cl3NO
分子量:282.59
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价格
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10mM*1mL in DMSO
询价
询价
100mg
询价
询价
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产品详情
生物活性:
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor with an IC50 of 3.3 μM. Antitrypanosomal agent 1 inhibits glutathione reductase (GR) (IC50=64.8 μM) and T. brucei (EC50=1 μM). Antitrypanosomal agent 1 has anti-trypanosomal activity.

体外研究:
Antitrypanosomal agent 1 (compound 8a) has an selectivity for TR (GR IC50/TR IC50) of 20.
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