产品
编 号：F445340
分子式：C9H10ClNO2
分子量：199.63
分子式：C9H10ClNO2
分子量：199.63
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
500mg
320
In-stock
1g
400
In-stock
结构图
CAS No: 7424-00-2
产品详情
生物活性：
Fenclonine is a selective and irreversible tryptophan hydroxylase inhibitor, which is a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine can be used in carcinoid syndrome research.
体内研究：
Fenclonine (intraperitoneal injection; 100 mg/kg; once daily; 3 d) treatment can inhibit Morphine-induced anti-nociceptive activity.?Fenclonine (intraperitoneal injection; 300 mg/kg; once daily; 3 d) pretreatment completely abolishes the effects of a 50?mg/kg dose of Paracetamol.Animal Model:Wistar albino rats of either sex and weighing between 80 and 100 g
Dosage:100 mg/kg
Administration:Intraperitoneal injection; 100 mg/kg; once daily; 3 days
Result:Inhibited the antinociceptive activity of Morphine by 41.5%.
Animal Model:Male Swiss mice (22–25 g)
Dosage:300 mg/kg
Administration:Intraperitoneal injection; 300 mg/kg; once daily; 3 days
Result:Inhibited the effects of Paracetamol in depression-like and compulsion-like behavior.
Fenclonine is a selective and irreversible tryptophan hydroxylase inhibitor, which is a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine can be used in carcinoid syndrome research.
体内研究：
Fenclonine (intraperitoneal injection; 100 mg/kg; once daily; 3 d) treatment can inhibit Morphine-induced anti-nociceptive activity.?Fenclonine (intraperitoneal injection; 300 mg/kg; once daily; 3 d) pretreatment completely abolishes the effects of a 50?mg/kg dose of Paracetamol.Animal Model:Wistar albino rats of either sex and weighing between 80 and 100 g
Dosage:100 mg/kg
Administration:Intraperitoneal injection; 100 mg/kg; once daily; 3 days
Result:Inhibited the antinociceptive activity of Morphine by 41.5%.
Animal Model:Male Swiss mice (22–25 g)
Dosage:300 mg/kg
Administration:Intraperitoneal injection; 300 mg/kg; once daily; 3 days
Result:Inhibited the effects of Paracetamol in depression-like and compulsion-like behavior.
产品资料
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