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编 号:F443931
分子式:C26H30O10
分子量:502.51
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生物活性:
Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and anti-aromatase (IC50=25.60 μM) properties.

体外研究:
Isolimonexic acid (200 μM; 72 hours) exhibits cytotoxicity on MCF-7 cells and shows no cytotoxicity against the MDA-MB-231 cell lines.Isolimonexic acid (50 μg/ml; 48, 96 and 144 hours) exhibits cell growth inhibition of Panc-28 cells in a time-dependent manner.And it percent inhibition comparison to control cells are 21%, 68%, and 90.58% at 48, 72, and 144 h, respectively.
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