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编 号：F443656
分子式：C19H18N2O4
分子量：338.36
分子式：C19H18N2O4
分子量：338.36
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CAS No: 73815-11-9
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生物活性：
Cimoxatone (MD 780515) is a reversible, selectively and orally active type A monoamine oxidase (MAO-A) inhibitor. Cimoxatone enhances the anorectic action of Serotonin (HY-B1473A).
体内研究：
Cimoxatone (20 mg/kg; p.o.) 增强 5-HT (1 mg/kg; s.c.) 对大鼠的厌食作用。Animal Model:250-300 g, Adult male Wistar rats
Dosage:20 mg/kg
Administration:P.o.
Result:Significiantly reduced sucrose intake induced by 1 mg/kg 5-HT or its vehicle injected 2 and 24 h later, significantly enhanced the anorectic action of 5-HT at 2 h but not at 24 h.
Cimoxatone (MD 780515) is a reversible, selectively and orally active type A monoamine oxidase (MAO-A) inhibitor. Cimoxatone enhances the anorectic action of Serotonin (HY-B1473A).
体内研究：
Cimoxatone (20 mg/kg; p.o.) 增强 5-HT (1 mg/kg; s.c.) 对大鼠的厌食作用。Animal Model:250-300 g, Adult male Wistar rats
Dosage:20 mg/kg
Administration:P.o.
Result:Significiantly reduced sucrose intake induced by 1 mg/kg 5-HT or its vehicle injected 2 and 24 h later, significantly enhanced the anorectic action of 5-HT at 2 h but not at 24 h.
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