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编 号：F443629
分子式：C20H24O4
分子量：328.4
分子式：C20H24O4
分子量：328.4
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CAS No: 7380-39-4
产品详情
生物活性：
5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and ?antibacterial?activities. 5-Geranoxy-7-methoxycoumarin induces cell apoptosis.
体外研究：
5-Geranoxy-7-methoxycoumarin (12.5-200 μM; 24-72 hours) induces a significant inhibition of cell growth in a time-dependent manner in SW480 cells.5-Geranoxy-7-methoxycoumarin (50 μM;48 hours) promotes DNA fragmentation and causes apoptosis through inhibition of the p38 MAPK signaling pathway in SW480 cells.5-Geranoxy-7-methoxycoumarin (50 μM; 24-48 hours) increases the percentage of cells in the sub G1/G0 phase from 5.3% (in control cells) to 18% after 48 h incubation.
5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and ?antibacterial?activities. 5-Geranoxy-7-methoxycoumarin induces cell apoptosis.
体外研究：
5-Geranoxy-7-methoxycoumarin (12.5-200 μM; 24-72 hours) induces a significant inhibition of cell growth in a time-dependent manner in SW480 cells.5-Geranoxy-7-methoxycoumarin (50 μM;48 hours) promotes DNA fragmentation and causes apoptosis through inhibition of the p38 MAPK signaling pathway in SW480 cells.5-Geranoxy-7-methoxycoumarin (50 μM; 24-48 hours) increases the percentage of cells in the sub G1/G0 phase from 5.3% (in control cells) to 18% after 48 h incubation.
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