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编 号:F442804
分子式:C21H20BrNO6
分子量:462.29
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5mg
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10mg
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生物活性:
(-)-Bicuculline methobromide (l-Bicuculline methobromide) is a potent GABAA receptor antagonist. (-)-Bicuculline methobromide blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons.

体内研究:
(-)-BicucuLline methobromide (0.6 nmol/rat) 减弱 Neurotropin 的抗痛觉异常作用。Animal Model:Rat L5-SNL model
Dosage:0.6 nmol/rat
Administration:Intrathecal injection, 5 minutes before administration of Neurotropin (100 NU/kg, i.v.)
Result:Attenuated the antiallodynic effect of Neurotropin.
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