产品
编 号:F442346
分子式:C10H12ClN3O3S
分子量:289.74
产品类型
结构图
CAS No: 73-49-4
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生物活性:
Quinethazone is an orally active diuretic agent and is also a weak inhibitor of carbonic anhydrase. Quinethazone can be used for hypertension research.
体内研究:
Quinethazone (50 mg/kg; p.o.; daily for 2 weeks) lowers blood pressure of renal hypertensive rats in association with a decrease in potassium but no change in water or sodium contents of aorta wall.Animal Model:Five- to 6-week-old Long Evans male rats, hypertension model
Dosage:50 mg/kg
Administration:Oral, daily for 2 weeks
Result:Had no significant effect on sodium or water distribution in arterial tissue of hypertensive rats, but decreased approximate 20% intra-cellular content of potassium