产品
编 号：F441466
分子式：C6H14ClNO4
分子量：199.63
分子式：C6H14ClNO4
分子量：199.63
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 73285-50-4
产品详情
生物活性：
1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin hydrochloride suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin hydrochloride possesses antihyperglycemic, anti-obesity, and antiviral features.
体内研究：
1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) (20-80 mg/kg; i.v.; daily for four weeks) shows anti-obesity effect .1-Deoxynojirimycin hydrochloride significantly improves insulin sensitivity via activating insulin signaling PI3K/AKT pathway in skeletal muscle of db/db mice.Animal Model:db/db mice
Dosage:20, 40, 80 mg/kg
Administration:Intravenously; daily for four weeks
Result:Significantly reduced body weight, blood glucose and serum insulin levels; Improved glucose tolerance and insulin tolerance.
1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin hydrochloride suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin hydrochloride possesses antihyperglycemic, anti-obesity, and antiviral features.
体内研究：
1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) (20-80 mg/kg; i.v.; daily for four weeks) shows anti-obesity effect .1-Deoxynojirimycin hydrochloride significantly improves insulin sensitivity via activating insulin signaling PI3K/AKT pathway in skeletal muscle of db/db mice.Animal Model:db/db mice
Dosage:20, 40, 80 mg/kg
Administration:Intravenously; daily for four weeks
Result:Significantly reduced body weight, blood glucose and serum insulin levels; Improved glucose tolerance and insulin tolerance.
产品资料
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