产品
编 号:F440182
分子式:C10H13Li4N6O12P3
分子量:529.93
产品类型
结构图
CAS No: 72957-42-7
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产品详情
生物活性:
AMP-PNP tetralithium (Adenylyl-imidodiphosphate tetralithium) is a non-hydrolysable analogue of ATP and inhibits KATP channels.
体外研究:
AMP-PNP (5 to 500 μM; Li salt) reduced the open-probability po of KATP channels and decreases the single-channel currents at high nucleotide concentrations by approximately 10%.AMP-PNP inhibits KATP channels of ventricular myocytes and of pancreatic β-cells both in the absence and presence of Mg2+ ions.