产品
编 号:F440173
分子式:C24H26N2O4
分子量:406.47
产品类型
结构图
CAS No: 72956-09-3
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产品详情
生物活性:
Carvedilol (BM 14190) is a non-selective β/α-1 blocker. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome.
体外研究:
Carvedilol 抑制体外活化的人嗜中性粒细胞产生超氧化物,IC50 为 28 μM。Carvedilol 可在无细胞系统中清除氧自由基,IC50 为 25 μM。