产品
编 号：F438800
分子式：C14H23N5O6
分子量：357.36
分子式：C14H23N5O6
分子量：357.36
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CAS No: 72571-82-5
产品详情
生物活性：
Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections.
体内研究：
Pipemidic acid (50 mg/kg) trihydrate is absorbed well by the oral route, and the peak levels in plasma ranged from 4 to 12 μg/mL in mice, rats, dogs, monkeys.The mean lethal dose of Pipemidic acid trihydrate after a single oral dose was more than 16000 mg/kg in mice.
体外研究：
Pipemidic acid trihydrate is an inhibitor of DNA gyrase that is a bacterial enzyme which catalyzes the ATP-dependent negative supercoiling of DNA.
Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections.
体内研究：
Pipemidic acid (50 mg/kg) trihydrate is absorbed well by the oral route, and the peak levels in plasma ranged from 4 to 12 μg/mL in mice, rats, dogs, monkeys.The mean lethal dose of Pipemidic acid trihydrate after a single oral dose was more than 16000 mg/kg in mice.
体外研究：
Pipemidic acid trihydrate is an inhibitor of DNA gyrase that is a bacterial enzyme which catalyzes the ATP-dependent negative supercoiling of DNA.
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