产品
编 号:F437004
分子式:C55H80N16O16
分子量:1221.32
产品类型
结构图
CAS No: 720710-69-0
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产品详情
生物活性:
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1. (Ex/Em=325 nm/400 nm)
体外研究:
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH26 对胶原酶 (MMP-1、MMP-8、MMP-13) 和 MT1-MMP (MMP-14) 的特异性常数 (kcat/Km) 比 FS-1 增加了 2-9 倍,或 3 倍。