产品
编 号:F435400
分子式:C36H51NO11
分子量:673.79
产品类型
结构图
CAS No: 71-62-5
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产品详情
生物活性:
Veratridine (3-Veratroylveracevine) is a plant neurotoxin, a voltage-gated sodium channels (VGSCs) agonist. Veratridine inhibits the peak current of Nav1.7, with an IC50 of 18.39?μM. Veratridine regulates sodium ion channels mainly by activating sodium ion channels, preventing channel inactivation and increasing sodium ion flow.
体外研究:
Veratridine (0.25 mM and 1 mM; 24 h) 导致所有细胞死亡。Veratridine (0.001-100 μM) 产生河豚毒素敏感反应。