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编 号:F433036
分子式:C22H20N4OS2
分子量:420.55
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结构图
CAS No: 709002-46-0
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生物活性:
SirReal2 is a potent, isotype-selective Sirt2 inhibitor with an IC50 value of 140?nM and has very little effect on the activities of Sirt3-5. SirReal2 leads to tubulin hyperacetylation in HeLa cells and induces destabilization of the checkpoint protein BubR1.