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编 号：F432730
分子式：C25H24N8O7S2
分子量：612.64
分子式：C25H24N8O7S2
分子量：612.64
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CAS No: 70797-11-4
产品详情
生物活性：
Cefpiramide (SM-1652) free acid is a semisynthetic cephalosporin with broad-spectrum antibacterial activity. Cefpiramide free acid shows strong antibacterial effect on both gram-positive bacteria and gram-negative bacteria. Cefpiramide free acid is moderately susceptible to β-lactamase.
体内研究：
Cefpiramide (25 mg/kg; i.v.; once) shows anti-Streptococcus pneumoniae activity in experimental pneumococcal meningitis.Cefpiramide (25 mg/kg; i.v.; once) reduces bacteria in CSF more than 10 CFU/ml.Animal Model:New Zealand white male rabbits(2-3 kg).
Dosage:25 mg/kg
Administration:Intravenous injection; once.
Result:Anti-Streptococcus pneumoniae.
体外研究：
Cefpiramide (0-2048 μg/mL; 16-18 hours) shows good activity to against most non-fermentative Gram-negative bacilli and Enterococci (32 μg/mL with 97% inhibition).Cefpiramide (0-2048 μg/mL; 16-18 hours) exhibits high effective to against Pseudomonas aeruginosa with MIC[50] and MIC[90] values of 4 μg/mL and 16 μg/mL separately.
Cefpiramide (SM-1652) free acid is a semisynthetic cephalosporin with broad-spectrum antibacterial activity. Cefpiramide free acid shows strong antibacterial effect on both gram-positive bacteria and gram-negative bacteria. Cefpiramide free acid is moderately susceptible to β-lactamase.
体内研究：
Cefpiramide (25 mg/kg; i.v.; once) shows anti-Streptococcus pneumoniae activity in experimental pneumococcal meningitis.Cefpiramide (25 mg/kg; i.v.; once) reduces bacteria in CSF more than 10 CFU/ml.Animal Model:New Zealand white male rabbits(2-3 kg).
Dosage:25 mg/kg
Administration:Intravenous injection; once.
Result:Anti-Streptococcus pneumoniae.
体外研究：
Cefpiramide (0-2048 μg/mL; 16-18 hours) shows good activity to against most non-fermentative Gram-negative bacilli and Enterococci (32 μg/mL with 97% inhibition).Cefpiramide (0-2048 μg/mL; 16-18 hours) exhibits high effective to against Pseudomonas aeruginosa with MIC[50] and MIC[90] values of 4 μg/mL and 16 μg/mL separately.
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