产品
编 号:F432511
分子式:C20H24N2
分子量:292.42
产品类型
结构图
CAS No: 70713-45-0
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产品详情
生物活性:
Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.
体内研究:
In hypoventilation hypoxia, aligeron (5 mg/kg i.v.) and cinnarizine increase cortical resistance to hypoxia and accelerated the recovery of cortical bioelectrical activity. In KCl- and AMP-induced depressions aligeron shows a protective effect manifested in a decrease of the degree and duration of the depression.
体外研究:
Aligeron shows a broad spectrum of antagonistic action against different spasmogens in different isolated organs. The experiments on isolated perfused rabbit artery shows the antagonistic action of aligeron against the vasoconstrictor effects of noradrenaline and adrenaline.