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编 号:F431734
分子式:C17H20N2O5S
分子量:364.42
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10mM*1mL in DMSO
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5mg
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10mg
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50mg
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100mg
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生物活性:
ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1' pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM).

体外研究:
ARP-100 (50 nM) shows a significant reduction in the total number of invasive elongations.
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