产品
编 号:F431139
分子式:C2H5N5O3
分子量:147.09
产品类型
结构图
CAS No: 70-25-7
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产品详情
生物活性:
Methylnitronitrosoguanidine (MNNG) is an orally active alkylating agent with toxic and mutagenic effects. Methylnitronitrosoguanidine can as a carcinogen and mutagen. 50% water content, specifications are based on dry weight.
体内研究:
Methylnitronitrosoguanidine (MNNG;200 mg/kg;po) 刺激 Wistar 白化大鼠并增加胃癌大鼠的数量。Animal Model:Male Wistar albino rats
Dosage:200 mg/kg
Administration:Oral administration, at 0 and 14th days
Result:Had the incidence of gastric cancer in Wistar albino rats is 100%.
体外研究:
Methylnitronitrosoguanidine (MNNG,0-1100 nM;24 h) 对 3 种人二倍体淋巴母细胞系 MIT-2、WI-L2 和 GM 130 具有毒性和致突变作用。