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编 号:F051642
分子式:C19H22ClNO4
分子量:363.84
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生物活性:
SB-206606, a stereoisomer of BRL 37344, is a potentially specific, beta 3-adrenergic receptor (β3-AR) ligand. The affinity of [3H]SB 206606 is 76 times higher for the β3-AR than for the beta 1/beta 2-adrenergic receptors.

体外研究:
[3H]SB-206606 binding to membranes from Chinese hamster ovary K1 cells transfected with the rat β3-AR with a Kd value of 58 nM.[3H]SB-206606 binding to brown adipose tissue where beta 1-, beta 2-, and beta 3-adrenergic receptor subtypes are known to coexist with a Kd value of 38 nM.
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