产品
编 号：F429689
分子式：C34H38O13
分子量：654.66
分子式：C34H38O13
分子量：654.66
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 697235-39-5
产品详情
生物活性：
Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia perviridis, and is a specific eIF4A-targeting translation inhibitor, with antitumor activity.
体外研究：
Episilvestrol is a specific eIF4A-targeting translation inhibitor, with antitumor activity. Episilvestrol is cytotoxic activity against several human cancer cell lines, such as Lu1, LNCaP, MCF-7 andHUVEC cells, with ED50s of 3.8, 3.8, 5.5 and 15.3 nM, respectively. The GI50s of Episilvestrol against the cell proliferation of NCI-H460 and MCF-7 cels are 17.96 nM and 17.96 nM after first test and 15.6 nM and 18.7 nM after 2 months via SRB assay. Episilvestrol also suppresses HK1 cells and EBV-positive C666.1 NPC cells.
Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia perviridis, and is a specific eIF4A-targeting translation inhibitor, with antitumor activity.
体外研究：
Episilvestrol is a specific eIF4A-targeting translation inhibitor, with antitumor activity. Episilvestrol is cytotoxic activity against several human cancer cell lines, such as Lu1, LNCaP, MCF-7 andHUVEC cells, with ED50s of 3.8, 3.8, 5.5 and 15.3 nM, respectively. The GI50s of Episilvestrol against the cell proliferation of NCI-H460 and MCF-7 cels are 17.96 nM and 17.96 nM after first test and 15.6 nM and 18.7 nM after 2 months via SRB assay. Episilvestrol also suppresses HK1 cells and EBV-positive C666.1 NPC cells.
产品资料
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