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编 号：F429270
分子式：C16H25N5O3
分子量：335.4
分子式：C16H25N5O3
分子量：335.4
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CAS No: 69579-13-1
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生物活性：
RGH-5526 (GYKI-11679) is a new antihypertensive agent.
体内研究：
RGH-5526 (GYKI-11679) is a new antihypertensive agent. Results show a sharp (61%) reduction in the hypothalamic Noradrenaline (NA) level 2 h after the administration of 10 mg/kg of RGH-5526, and this effect lasts for 4 to 6 h. It is demonstrated that RGH-5526 exerts a greater NA lowering effect in the hypothalamus than in the periphery. RGH-5526 does not influence the hypothalamic monoamine oxidase (MAO)-activity following prolonged treatment.
RGH-5526 (GYKI-11679) is a new antihypertensive agent.
体内研究：
RGH-5526 (GYKI-11679) is a new antihypertensive agent. Results show a sharp (61%) reduction in the hypothalamic Noradrenaline (NA) level 2 h after the administration of 10 mg/kg of RGH-5526, and this effect lasts for 4 to 6 h. It is demonstrated that RGH-5526 exerts a greater NA lowering effect in the hypothalamus than in the periphery. RGH-5526 does not influence the hypothalamic monoamine oxidase (MAO)-activity following prolonged treatment.
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