产品
编 号：F427365
分子式：C20H17ClN4OS
分子量：396.89
分子式：C20H17ClN4OS
分子量：396.89
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 689297-68-5
产品详情
生物活性：
KV2 channel inhibitor-1 is a selective KV2 channel inhibitor with IC50s of 0.2 μM and 0.41 μM for KV2.1 and KV2.2, respectively. KV2 channel inhibitor-1 possesses good selectivity over KV1.2 (IC50>10 μM). KV2 channel inhibitor-1 is >10-fold selective over NaV channels and other KV channels and displays weak activity on CaV channels.
体外研究：
KV2 channel inhibitor-1 (compound A1; 0.3, 1, 3 μM; 0-3000s) 抑制大鼠胰岛素瘤 INS-1 细胞中的 KV 电流。KV2 channel inhibitor-1 在 0.3 μM 时平均阻断 INS-1 KV 电流 71%，在 3 μM 时平均阻断 84%。
KV2 channel inhibitor-1 is a selective KV2 channel inhibitor with IC50s of 0.2 μM and 0.41 μM for KV2.1 and KV2.2, respectively. KV2 channel inhibitor-1 possesses good selectivity over KV1.2 (IC50>10 μM). KV2 channel inhibitor-1 is >10-fold selective over NaV channels and other KV channels and displays weak activity on CaV channels.
体外研究：
KV2 channel inhibitor-1 (compound A1; 0.3, 1, 3 μM; 0-3000s) 抑制大鼠胰岛素瘤 INS-1 细胞中的 KV 电流。KV2 channel inhibitor-1 在 0.3 μM 时平均阻断 INS-1 KV 电流 71%，在 3 μM 时平均阻断 84%。
产品资料
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