产品
编 号:F427202
分子式:C17H17Cl2FN4O4S
分子量:463.31
产品类型
结构图
CAS No: 688763-64-6
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产品详情
生物活性:
Elubrixin (SB-656933) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation.
体外研究:
Elubrixin has an inhibitory effect on neutrophils in a dose-dependent fashion.