产品
编 号:F427092
分子式:C14H9Cl3
分子量:283.58
产品类型
结构图
CAS No: 688348-25-6
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产品详情
生物活性:
PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an Ki of 1.2±0.4 nM.
体外研究:
PDM2 (Compound 4b) exhibits a Ki of 1.2±0.4 nM for AhR and no affinity for estrogen receptor (ER), confirming that replacement of hydroxyl with chloride abolished binding on ER and increased dramatically the affinity for AhR.