产品
编 号:F425306
分子式:C20H20O5
分子量:340.37
产品类型
结构图
CAS No: 68236-13-5
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产品详情
生物活性:
(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface.
体外研究:
(2S)-6-Prenylnaringenin (6-Prenylnaringenin) displays a modulatory activity at low micromolar concentrations. (2S)-6-Prenylnaringenin potentiates GABA-induced displacement of [3H]EBOB binding in a concentration-dependent manner where the IC50 value for this potentiation in native GABAA receptors is 3.7 μM, respectively.