产品
编 号：F425097
分子式：C20H37NO2
分子量：323.51
分子式：C20H37NO2
分子量：323.51
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CAS No: 68171-52-8
产品详情
生物活性：
Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1（CB1）and CB2 receptors, and inhibits the binding of [3H]CP-55,940 with Kis of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time.
体内研究：
Linoleoyl ethanolamide (0.1 mg-0.2 mg; challenged by painting the inner and outer surfaces of both sides of their ears) suppresses DNFB-induced ear swelling in BALB/c mice.
体外研究：
Linoleoyl ethanolamide competitivelyinhibitsthehydrolysisofanandamide and maybeinvolvedintheregulationoffoodintakebyselectiveprolongationoffeedinglatencyandpost-mealinterval.
Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1（CB1）and CB2 receptors, and inhibits the binding of [3H]CP-55,940 with Kis of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time.
体内研究：
Linoleoyl ethanolamide (0.1 mg-0.2 mg; challenged by painting the inner and outer surfaces of both sides of their ears) suppresses DNFB-induced ear swelling in BALB/c mice.
体外研究：
Linoleoyl ethanolamide competitivelyinhibitsthehydrolysisofanandamide and maybeinvolvedintheregulationoffoodintakebyselectiveprolongationoffeedinglatencyandpost-mealinterval.
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