产品
编 号：F423772
分子式：C24H30F2O6
分子量：452.49
分子式：C24H30F2O6
分子量：452.49
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
500mg
480
In-stock
1g
744
In-stock
5g
2604
In-stock
结构图
CAS No: 67-73-2
产品详情
生物活性：
Fluocinolone is a glucocorticoid glucocorticoid receptor agonist. Fluocinolone is effective in preventing both lipid accumulation and inflammation. Fluocinolone can promote the proliferation of DPCs and has the potential role in repairing injured pulp tissues. Fluocinolone can be used to study the prevention of chemotherapy-induced peripheral neuropathy caused by Paclitaxel (HY-B0015).
体内研究：
Fluocinolone (500 μg/kg, Intraperitoneal injection, once a day for 2 weeks) 在 PTX 诱导的小鼠模型中，预防了显著的周围神经病变的发展。Animal Model:PTX-induced peripheral neuropathy model
Dosage:500 μg/kg
Administration:Intraperitoneal injection (i.p.)
Result:Prevented a marked reduction in intraepidermal nerve fibers density in the plantar surface of the hind paws.
体外研究：
Fluocinolone 0.1-50 μg/mL, 2 days) 可提高泡沫细胞的存活率。Fluocinolone (0.1-50 μg/mL, 2 days) 抑制炎性细胞因子分泌并减少胆固醇酯积累。Fluocinolone (0.1-100 μmol/L, 24 h) 促进 DPCs 增殖。Fluocinolone (1-10 μmol/L, 7 days) 促进 BSP、OCN、DSPP 和 Wnt4 的表达，上调 Wnt4 和牙本质特异性标志牙本质涎磷蛋白的表达。
Fluocinolone is a glucocorticoid glucocorticoid receptor agonist. Fluocinolone is effective in preventing both lipid accumulation and inflammation. Fluocinolone can promote the proliferation of DPCs and has the potential role in repairing injured pulp tissues. Fluocinolone can be used to study the prevention of chemotherapy-induced peripheral neuropathy caused by Paclitaxel (HY-B0015).
体内研究：
Fluocinolone (500 μg/kg, Intraperitoneal injection, once a day for 2 weeks) 在 PTX 诱导的小鼠模型中，预防了显著的周围神经病变的发展。Animal Model:PTX-induced peripheral neuropathy model
Dosage:500 μg/kg
Administration:Intraperitoneal injection (i.p.)
Result:Prevented a marked reduction in intraepidermal nerve fibers density in the plantar surface of the hind paws.
体外研究：
Fluocinolone 0.1-50 μg/mL, 2 days) 可提高泡沫细胞的存活率。Fluocinolone (0.1-50 μg/mL, 2 days) 抑制炎性细胞因子分泌并减少胆固醇酯积累。Fluocinolone (0.1-100 μmol/L, 24 h) 促进 DPCs 增殖。Fluocinolone (1-10 μmol/L, 7 days) 促进 BSP、OCN、DSPP 和 Wnt4 的表达，上调 Wnt4 和牙本质特异性标志牙本质涎磷蛋白的表达。
产品资料
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