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编 号:F422794
分子式:C7H17N2O2
分子量:161.22
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生物活性:
Bethanechol (Carbamyl-β-methylcholine), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system.

体内研究:
Bethanechol (2-12 mg/kg; i.p.) induces drinking and increased urine output of rats in a dose-dependent fashion.Animal Model:Female rats of the Blue Spruce Farms (Sprague-Dawley) (280-330 g)
Dosage:2 mg/kg, 4 mg/kg, 8 mg/kg, 12 mg/kg
Administration:Intraperitoneal injection
Result:Increased water intake during the first hr in a dose-dependent fashion up to the highest dose administered (12 mg/kg).

体外研究:
Bethanechol (0.3-300 μM) significantly reduces ileal pacemaker potentials.
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